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Best antiaging supplement
Reserveage Organics Resveratrol 250 mg: A super-potent weapon in your antiaging arsenal, this supplement combines cell-protective antioxidants from USDA Organic red-wine grapes, seeds, vine, and root extract. Also with anti-inflammatory quercetin.
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Best blood sugar balance supplement
Natural Factors WellBetX PGX Plus Mulberry: Taking PGX’s proprietary soluble fiber blend with a meal may reduce glycemic impact of the meal and extend satiety; mulberry extract helps balance blood sugar.
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Best bone health supplement
Natural Vitality OsteoCalm: This bioavailable, orange-flavored liquid delivers the ideal 1:1 ratio of calcium to magnesium, plus key vitamins D3 and K2.
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Best brain health supplement
Bluebonnet Power Thought: Comprehensive nutrients to improve cognition: B vitamins, dimethylaminoethanol (DMAE), L-glutamine, phosphatidylcholine (PC), phosphatidylserine (PS), and more.
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Best cleansing & detox supplement
Enzymatic Therapy Whole Body Cleanse: This popular 10-day program includes a cleansing formula, a fiber mix with glucomannan (konjac root), and probiotic Acidophilus Pearls, which work together to remove toxins and recharge digestive health.
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Best cold & flu supplement
American Health Ester-C 1,000 mg with Citrus Bioflavonoids: Vitamin C can reduce cold symptoms, but you need to take a lot: 2,000–6,000 grams daily in divided doses. This nonacidic form may be better tolerated and absorbed. It’s also available in new 1000-mg effervescent packets.
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Best digestion supplement
Enzymedica Digest Gold + Probiotics: Here’s a complete digestive solution in one capsule: 13 digestive enzymes combined with 500 million CFUs of specially coated probiotics.
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Best energy supplement
Solgar D-Ribose Powder: Studies show this simple sugar heightens cellular energy and can help with fibromyalgia.
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Best eye health supplement
LifeSeasons Visibili-T Eye Health Complex: This new supplement supports macular health and protects from UV light with lutein, zeaxanthin, and bilberry.
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Best fiber/laxative supplement
ReNew Life CleanseMore: This gently detoxifying, laxative formula contains magnesium and herbs (aloe, rhubarb, slippery elm, marshmallow), and no fillers or harsh ingredients.
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Best green foods supplement
Amazing Grass Green SuperFood Raw Reserve: With more than 25 billion probiotic CFUs per serving, this tasty organic green foods powder also includes antioxidant acaí and maca.
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Best heart health supplement
Wakunaga Kyolic CoQ10 Formula 110: Two heart-health champions together: a proprietary, odorless, aged garlic extract and coenzymeQ10, which increases energy in heart tissue.
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Best herbal supplement
Gaia Herbs Adrenal Health: This popular herbal blend bolsters adrenal gland function to combat chronic stress. Gaia products are vegan, tested for purity and potency, and traceable through the online Meet Your Herbs program.
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Best homeopathic supplements
Heel Traumeel: This topical pain remedy combines 14 active ingredients that work with the body’s own resources to relieve bruising and muscle and joint pain.
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Best immunity supplement
Now Foods EpiCor Plus Immunity: EpiCor, a proprietary baker’s yeast derivative that helps regulate immune response, joins vitamins C and D, zinc, and olive leaf extract.
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Best joint health supplement
Europharma Terry Naturally Healthy Knees and Joints: This new formula maintains healthy cartilage and joint mobility with anti-inflammatory ingredients: a proprietary, bioavailable curcumin complex (derived from turmeric), along with boswellia, fructoborate, and vitamin D.
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Best kids’ multivitamin
Hero Nutritionals Sugar Free Yummi Bears Multi-Vitamin & Mineral: Look, Mom, no sugar! The first children’s gummy sweetened with the prebiotic inulin and luo han guo fruit, it provides 16 key nutrients in age-appropriate doses.
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Best kids’ health supplements
Carlson For Kids Cod Liver Oil: This classic, lemon-flavored liquid supports brain and eye development with a high DHA dose, along with EPA and vitamins A and D3.
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Best men’s multivitamin
Source Naturals Life Force Multiple: This complete multi supports cellular energy, as well as the brain, immunity, and vision, with high-dose B vitamins, coQ10, adaptogenic herbs, and antioxidants.
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Best men’s health supplements
Now Foods Clinical Strength Prostate Health: Sustains prostate function with saw palmetto, beta-sitosterol, and lycopene. Other helpful ingredients: zinc, selenium, quercetin, and vitamin D.
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Best metabolism/weight loss supplement
Country Life 7-Keto Trim: Growing research shows the DHEA metabolite 7-keto can boost metabolism—without DHEA’s potential side effects, because 7-keto can’t metabolize into sex hormones.
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Best new supplement product
i-Health Ovega-3: The first vegan omega-3 supplement with not only DHA but also EPA, Ovega-3 is sourced from tank-grown algae, so there’s no worry about sustainability or contaminants.
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Best omega-3 supplement
Nordic Naturals Ultimate Omega Xtra: Two convenient softgels offer a purified, concentrated 1,400-mg dose of EPA and DHA, plus 1,000 IU vitamin D3 to reinforce bone and immune health.
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Best prenatal multivitamin
New Chapter Perfect Prenatal: Whole-food, probiotic nutrients and herbs support digestion and healthy pregnancy. A cruciferous-vegetables blend supports breast health.
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Best probiotic supplement
Garden of Life Raw Probiotics: These high-potency, multistrain formulas target health concerns by age and gender. The men’s formula, for instance, supports immunity during workouts.
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Best sleep supplement
Source Naturals NightRest with Melatonin: This effective formula offers the research-backed sleep hormone melatonin plus neurotransmitter regulator GABA and calming herbs.
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Best sports nutrition supplement
Sequel Naturals Vega Sport Performance System: Formulated by a triathlete using impressively clean, cutting-edge, and vegan ingredients, this line of products can help you prepare for, stay strong during, and recover from workouts.
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Best stress supplement
Natural Vitality Natural Calm: Mixed with water and taken morning and evening, this highly absorbable powder restores levels of often-deficient magnesium, relaxing the body and promoting regularity and sleep.
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Best value supplement
Nature’s Way Alive! Once Daily Multi-Vitamin: This traditional favorite offers great nutrient density for the price: high amounts of B vitamins, digestive enzymes, and green foods.
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Best vegan supplement
Sequel Naturals Vega Complete Whole Food Health Optimizer: A meticulous blend of plant-based, omega-rich protein sources (hemp, yellow pea, brown rice, flax, and chlorella), dairy-free probiotics, digestive enzymes, berry antioxidants, maca, and 100 percent RDIs of vitamins and minerals. Works as a meal replacement or a supplement.
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Best women’s multivitamin
MegaFood Women Over 40 One Daily: Like all MegaFood products, this whole-food and herb formula is tested free of pesticides, gluten, and soy. Beyond basics, it offers antioxidants, digestive enzymes, and immune-boosting herbs.
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Best women’s health
Enzymatic Therapy: Derived from cruciferous vegetables, diindolylmethane (DIM) improves estrogen metabolism, protecting against breast and other cancers.
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Unless you have a degree in medicine, or perhaps chemistry, trying to choose a dietary supplement by scrutinizing the bottle’s Facts Panel can feel like deciphering hieroglyphics. To simplify your search, our editors and medical experts studied the science behind the ingredients of the best-quality formulas out there and chose these favorites: the most innovative and effective supplements on the market today.
How were these supplements chosen?
Photos by Erin Manning